AOD-9604 vs Semaglutide
These two are popular fat-metabolism research compounds with nothing mechanistically in common. AOD-9604 is a growth-hormone fragment; semaglutide is a GLP-1 agonist. The comparison is really about two very different routes to the same research area.
| AOD-9604 | Semaglutide | |
|---|---|---|
| Compound class | Growth-hormone fragment (176-191) | GLP-1 receptor agonist |
| Primary target | Lipolytic GH fragment | GLP-1 receptor |
| Category | GLP-1 & Metabolic | GLP-1 & Metabolic |
| Administration | Daily subcutaneous | Weekly subcutaneous |
| Research focus | Fat metabolism without systemic GH effects | Appetite signaling & glycemic control |
Key differences
- Mechanism: AOD-9604 is a modified GH fragment (176-191) studied for lipolysis; semaglutide is a GLP-1 receptor agonist acting on appetite and glycemic signaling.
- Appetite: semaglutide directly influences appetite signaling; AOD-9604 is studied for fat metabolism without the broad GH or appetite effects.
- Dosing cadence: AOD-9604 research is typically daily; semaglutide is weekly.
- Effect profile: semaglutide has large, well-documented metabolic effects; AOD-9604 is a milder, more targeted lipolytic research tool.
Which is right for your research?
Semaglutide is the heavyweight appetite/glycemic compound; AOD-9604 is the lightweight GH-fragment option for lipolysis-focused research without incretin activity.
Frequently asked questions
Do AOD-9604 and semaglutide work the same way?
No. AOD-9604 is a growth-hormone fragment studied for fat metabolism, while semaglutide is a GLP-1 agonist that acts on appetite and glycemic pathways.
How often is each dosed in research?
AOD-9604 is typically dosed daily; semaglutide is dosed weekly.
Which has the larger effect?
Semaglutide has the larger, better-documented metabolic effect; AOD-9604 is a milder, more targeted lipolytic compound.
For Research Use Only. All products are sold as research chemicals for in-vitro laboratory study. Not for human consumption, medical, veterinary, or household use.